Brazilian researchers have found that a molecule in the venom of a type of snake inhibited coronavirus reproduction in monkey cells, a possible first step toward a drug to combat the virus causing COVID-19.
A study published in the scientific journal Molecules this month found that the molecule produced by the jararacussu pit viper inhibited the virus’s ability to multiply in monkey cells by 75%.
“We were able to show this component of snake venom was able to inhibit a very important protein from the virus,” said Rafael Guido, a University of Sao Paulo professor and an author of the study.
The molecule is a peptide, or chain of amino acids, that can connect to an enzyme of the coronavirus called PLPro, which is vital to the reproduction of the virus, without hurting other cells.
Already known for its antibacterial qualities, the peptide can be synthesized in the laboratory, Guido said in an interview, making the capture or raising of the snakes unnecessary.
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