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The show will see the actress step in for the original protagonist Jeremy Irons. In a modern take on David Cronenberg's cult horror classic of 1988, Weisz will be seen playing the double lead role of the Mantle twins, who share everything from drugs, lovers, to desire to do whatever it takes.

"I'm thrilled to be collaborating with the exceptionally talented (screenwriter) Alice Birch. I can't wait to go on this journey," Weisz said. Birch will write as well as executive produce it.

"This update to ‘Dead Ringers' explores the darker side of medicine, obsession, and the human condition, making it a compelling addition to our slate of original series," said Albert Cheng of Amazon Studios. "Dead Ringers" series will be available on Amazon Prime Video.

Meanwhile, Weisz will next appear with Scarlett Johansson in the upcoming "Black Widow".

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