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The Oscar winner took to Instagram on Sunday to share the update.
Berry, 54, will essay the role of a NASA astronaut-turned-administrator whose previous space mission holds a clue about an impending catastrophe.
"Officially out of #Quarantine - ready to get to work! #Moonfall here I come!" she captioned a selfie.
"Moonfall" follows the aftermath of when the moon is knocked from its orbit by a mysterious force and is on a collision course with Earth.
Life hangs in the balance and with just weeks to go before impact, a ragtag team is sent on a near impossible mission to land on the lunar surface and save humanity.
Patrick Wilson, Stanley Tucci, Josh Gad, and John Bradley also round the cast of "Moonfall".
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