Apart from Chennaiyin, Mumbai City FC, Odisha FC and Kerala Blasters FC will have their home games at the GMC Stadium. Hence, CFC will play 12 matches – nine home matches and three ‘away’ games – at the venue in the upcoming season. Two-time title-winner Chennaiyin is familiar with the ground, having used it for practice sessions in the previous editions, including the semi-final second leg and final in ISL 2019-20. The groupings have been done based on the ISL Season 6 league standings.

FC Goa, ATK Mohun Bagan and Bengaluru FC will play their home matches at the Jawaharlal Nehru Stadium in Fatorda while Jamshedpur FC, NorthEast United FC and Hyderabad FC will have their home games at the Tilak Maidan in Vasco.