The raw materials – known as active pharmaceutical ingredient (API) – for a large number of antibiotics like penicillin, azithromycin, doxycycline, amikacin, amoxicillin, ornidazole and dexamethasone sodium, etc. are supplied mostly from China. Due to factory closures there, pharma firms are finding it difficult to source raw materials and have thus increased the cost of paracetamol by about 40 per cent and azithromycin by 70 per cent.