Since her debut with 2013's Shoojit Sircar-directed Madras Cafe, Khanna has worked in Tamil and Telugu industries, featuring in movies like Bengal Tiger, Supreme, Jai Lava Kusa, Tholi Prema, Imaikkaa Nodigal and Prati Roju Pandage. She ventured into Malayalam movies with the 2017 action thriller Villain, co-starring veteran actor Mohanlal. Khanna said she is fascinated with the kind of risks the filmmakers from the Malayalam film industry take. Even artistes are constantly pushing the envelope with their work.