Reema Dodin and Shuwanza Goff will serve as deputy directors of the White House Office of Legislative Affairs.
Dodin has been working on the transition team already, leading its legislative engagement with lawmakers on Capitol Hill.
She also serves as deputy chief of staff and floor director to Illinois Sen Dick Durbin, the Democratic whip in the Senate.
Goff served as floor director for House Majority Leader Steny Hoyer. She helped craft the House Democrats' legislative agenda.
Dodin and Goff join Louisa Terrell, who was recently named the director of the White House Office of Legislative Affairs.
About a dozen other senior White House staffers also have been announced by the president-elect.
The team will be tasked with turning Biden's long list of campaign promises into legislative blueprints and ushering them through a closely divided House and Senate.
The first and biggest concern is expected to be a major coronavirus aid and response package after Biden takes office in January.