In the Warner Bros movie, to be written and directed by Jared Stern, Johnson will lend his voice to the character of Krypto the Super-Dog, according to The Hollywood Reporter.
"DC League of Super-Pets" will centre on Superman’s dog, who teams up with a flying cat to stop crime while the Man of Steel is on vacation.
Also joining the voice cast are actors Vanessa Bayer and Kate McKinnon.
Sam Levine will serve as co-director on the project, which Johnson is producing through his company Seven Bucks Productions, along with his partners Dany Garcia and Hiram Garcia.
Patricia Hicks, Jared Stern will also produce, while John Requa, Glenn Ficarra and Nicholas Stoller will serve as executive producers.
The movie will release in US theatres on May 20, 2022.